Dr. Michael G. Benton, PhD
Bernard S. Pressburg Professor
PhD, University of Wisconsin-Madison, 2007
MS, University of Alabama, 2002
BS in Biology, University of South Carolina, 1994
- Biochemical Engineering
- The role of DNA damage response in cancer prevention.
- Biosensors for the enhanced detection of carcinogens.
- Metabolic engineering of yeasts for increased ethanol production.
The recent proliferation of microarrays and other high throughput genomic screens has greatly increased our understanding of how gene expression is modulated under various cellular growth conditions. We are using these techniques to develop novel methods of monitoring real-time gene expression to characterize the cellular microenvironment. By monitoring gene expression changes within a cell, we can identify stresses present in the local environment, such as nutrient depletion and mutagenicity. Additionally, by modifying yeast gene expression patterns, we can improve metabolic performance to enhance the biomanufacturing of ethanol and other commodity products.